Archive for December, 2006
Thursday, December 14th, 2006
Rats given leptin injections had increased fat cell apoptosis (cell death) in both peripheral fat deposits and in bone marrow.
The leptin pathway is more complicated in humans than in rats, but future drugs may be able to partially duplicate this in humans.
Abstract
Posted in Hormones | No Comments »
Wednesday, December 13th, 2006
It is well known that the metabolic syndrome is accompanied by high blood triglycerides. But do high levels of these blood fats cause metabolic syndrome or are they a symptom of it?
Rabbits bred to be hypertriglyceridemic had more visceral fat and greater insulin resistance. Improving insulin sensitivity improves both triglycerides ...
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Tuesday, December 12th, 2006
Menopausal women experience a shift in fat distribution from a female pear shape to a more male-like apple shape due to visceral fat accumulation.
It has been speculated that a shift in androgen to estrogen ratio was a principal cause. This was confirmed by this study which showed DHT, the most ...
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Monday, December 11th, 2006
ALT is a liver enzyme commonly measured in liver panel lab tests. It also appears to be a marker for insulin sensitivity. It is also a very cheap lab test, compared to oral GTT or HbA1C.
An elevated ALT is associated with reduced insulin sensitivity and glucose tolerance and increased triglycerides.
Abstract
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Sunday, December 10th, 2006
Body fat distribution patterns are at least as important as BMI as a risk factor for heart disease. Waist to Hip Ratio (WHR) is a simple way to determine the degree of abdominal obesity.
Men of normal weight are still at risk of heart disease if their WHR is high. Women''s ...
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Saturday, December 9th, 2006
Leptin is part of our complex hunger signaling feedback system. Leptin levels are typically high in obese people, but because the signaling is impaired, they may still experience hunger even though body fat levels are high.
Children that were required to fast for diagnostic lab testing experienced a steady fall in ...
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