Archive for the ‘Hormones’ Category
Wednesday, October 25th, 2006
Compared to lean women, obese women have impaired leptin signaling leading to reduced insulin sensitivity. The defective signaling appears to be related to leptin receptors in subcutaneous fat but not visceral fat.
Leptin signals body fat levels to the brain, affecting appetite. High leptin levels are usually found in obese people ...
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Tuesday, October 24th, 2006
After high fat meals, women preferentially store fat in their legs. Storage in upper body subcutaneous tissue was similar in both sexes...suggesting that the men were preferentially storing the fat as visceral fat.
The researchers concluded that this was driven by increased LPL (lipoprotein lipase) activity in women, which is most ...
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Monday, October 23rd, 2006
The researchers used the drug bromocriptine (a D2R agonist) to simulate higher dopamine levels. Insulin sensitivity and fat oxidation improved.
Body weight did not improve during the time of the study, but improved insulin sensitivity and fat oxidation rates should improve body composition over time (the study only lasted 8 days). ...
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Friday, October 13th, 2006
Ghrelin, a gut hormone that stimulates appetite, is associated with improved insulin sensitivity. As the subjects lost weight, those with the best insulin sensitivity had the greatest increases in ghrelin.
The study did not look at appetite. Ghrelin increases appetite, but lower insulin levels decrease appetite. Perhaps it is a wash ...
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Wednesday, October 11th, 2006
Add fatty liver disease to the list of diseases associated with the metabolic sydrome (aka syndrome x).
Note that those with higher levels of intrahepatic fat (IHF) had lower levels of fat oxidation while fasting and less insulin sensitivity. High insulin levels basically shut down fat oxidation altogether, these subjects remained ...
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Monday, October 9th, 2006
The McAuley formula, which uses fasting insulin and triglycerides was proved to be a better predictor of insulin resistance than the HOMA formula, which uses fasting glucose and fasting insulin.
Triglycerides are actually a pretty good indicator alone, and relatively inexpensive as well (compared to fasting insulin).
Abstract
Related posts:Fructose Increases Insulin Resistance ...
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Friday, October 6th, 2006
Lower growth hormone levels reduce the ability to burn fat during workouts. This, most likely, is one of the many contributing factors to age related weight gain.
Growth hormone levels can be increased naturally with anaerobic exercise (especially weight training), maintaining low insulin levels and increasing dietary protein.
Abstract
Related posts:Resistance training and ...
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Monday, September 25th, 2006
This study out of Mexico shows the negative relationship between obesity and testosterone levels. SHBG was also lower and insulin higher in the obese group.
Fat cells are more metabolically active than once thought and produce many inflammator factors and some hormones...including estrogen metabolites. This, in combination with reduced androgen levels, ...
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